In this episode, we welcome Prof. Dr. Alexander Leber, one of the leading experts in internal medicine and cardiology. We discuss the causes and physiology of cardiovascular diseases, as well as treatment options and prevention tips.

#4 - Prof. Dr. Alexander Leber: The silent danger of cardiovascular diseases
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#88 - Longevity 101: The most important basics | Kristine Zeller at Men's Health
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Learn more#79 - The truth about TRT, peptides & co. - Adon Health doctor speaks out | Dr. Regaluto on men's health
In this episode of "Men's Health with Dr. Jonathan Apasu," Dr. Apasu speaks with Dr. Christoph Regalbuto , internist and one of Adon Health's first partner physicians, about modern testosterone replacement therapy (TRT) . Dr. Regalbuto has already treated several hundred men with sometimes severe testosterone deficiency – from exhausted family men to athletic men in their mid-30s who, despite exercise, diet, and sleep, are persistently lethargic, irritable, or weak. A central topic of the conversation is a large study of 133,000 patients , which impressively demonstrates that correctly adjusted TRT not only improves symptoms such as exhaustion, loss of libido, and mental fatigue, but also reduces the risk of heart attack, stroke, atrial fibrillation, prostate cancer , and even overall mortality . The two discuss why this data, while clear, is often slow to be adopted in the medical field—and why many men have unnecessary fears about prostate cancer or heart problems due to misinformation or outdated ideas. Another important point: Many doctors still believe that testosterone deficiency only affects overweight, inactive men. Dr. Regalbuto explains, however, that fit, young men are also frequently affected – and are not taken seriously in traditional practices. This is precisely where modern, evidence-based diagnostics and treatment come into play. The episode clearly distinguishes between medically supervised TRT and steroid abuse ("drugs") in bodybuilding . It explains why the risks often attributed to testosterone in the media stem almost exclusively from supraphysiological scenarios and have nothing to do with reputable TRT. Instead, the therapy focuses on finding a patient's individual "sweet spot" where vitality, mood, and libido are stable and side effects remain controlled. Another focus is the topic of fertility . The two explain why a current desire to have children is a clear contraindication for TRT and what alternatives exist—such as clomiphene, tamoxifen, hCG, or recombinant FSH —to support sperm production. At the same time, the fear of "lifelong dependence" is dispelled: studies show that both the body's own testosterone production and sperm production usually normalize within 9–12 months after discontinuing TRT. Finally, Dr. Regalbuto and Dr. Apasu address a trending topic: peptides such as BPC-157 and TB-500. They explain why animal studies are promising, but why there are hardly any human studies and no approved preparations – and why caution is advised despite potential benefits. This episode provides one of the most comprehensive German-language insights into the topics of testosterone deficiency, TRT, hormone health, heart and prostate risks, fertility, steroid abuse, and peptide therapy . Any man concerned about his long-term health or experiencing symptoms of testosterone deficiency will find well-founded, understandable, and scientifically proven answers here.
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