Testosterone is much more than muscles and libido, yet hardly any topic is so misunderstood. In this episode, Dr. Jonathan Apasu talks with Prof. Dr. Michael Zitzmann (University of Münster, Endocrinology and Andrology) about the crucial connections behind testosterone deficiency, diagnostics, and modern testosterone therapy, including genetics, SHBG, the estrogen-DHT balance, and the desire for children.
You will learn why some men have symptoms despite "normal" levels, why you can't simply "bump up the level," and what side effects threaten if used incorrectly. It will also cover what obesity really does to testosterone, and what new forms of therapy exist in the US that Germany does not have (yet).
Topics of this episode:
• Testosterone works in almost every body cell: bones, blood, vessels, brain
• Typical symptoms: fatigue, loss of libido, anxiety, poor recovery
• Total vs. free: SHBG, Vermeulen formula, and why "normal" is not always normal
• Androgen receptor genetics: CAG repeats and individual "normal values"
• Why testosterone without symptoms makes no sense and creates risks
• Desire for children: Why TRT stops sperm production and how long it can take to return
• Estrogen and DHT: Aromatase, body fat, and differences in preparations (gel vs. injection)
• Future: oral preparations, nasal spray, and why they are missing in Germany
If you really want to understand testosterone, medically correctly and without myths, be sure to listen in!

