Testosterone is much more than just muscles and libido, yet few topics are as misunderstood. In this episode, Dr. Jonathan Apasu speaks with Prof. Dr. Michael Zitzmann (University of Münster, Endocrinology and Andrology) about the crucial connections behind testosterone deficiency, diagnosis, and modern testosterone therapy, including genetics, SHBG, estrogen DHT balance, and fertility.
You'll learn why some men have symptoms despite "normal" values, why you can't simply "boost the value," and what side effects can occur with improper use. We also discuss what obesity really does to testosterone and what new therapies are available in the USA that Germany does not (yet) have.
Topics in this episode:
• Testosterone acts in almost every body cell: bones, blood, vessels, brain
• Typical symptoms: fatigue, loss of libido, anxiety, poor regeneration
• Total vs. free: SHBG, Vermeulen formula, and why "normal" isn't always normal
• Androgen receptor genetics: CAG repeats and individual "normal values"
• Why testosterone without symptoms makes no sense and creates risks
• Fertility: Why TRT stops sperm and how long recovery can take
• Estrogen and DHT: Aromatase, body fat, and product differences (gel vs. injection)
• Future: oral preparations, nasal spray, and why they are missing in Germany
If you truly want to understand testosterone, medically sound and without myths, be sure to listen in!



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