How much do our genes really determine how we age? In this episode, Prof. Dr. Bernd Kleine-Gunk explains why our DNA remains largely unchanged, but the activity of our genes can be influenced by epigenetics. Lifestyle, diet, exercise, sleep, and stress affect which genetic information is read or blocked.
Together with Dr. Jonathan Apasu, he discusses how epigenetic changes occur, why experiences may even shape subsequent generations, and how so-called epigenetic clocks determine biological age. It also addresses the question of whether aging processes could not only be slowed down in the future, but partially reversed through epigenetic reprogramming.
Topics of this episode:
- What distinguishes epigenetics from the classic genetic code
- How diet, exercise, sleep, and stress influence our gene activity
- Why epigenetic changes may be inherited
- What distinguishes biological age from chronological age
- How epigenetic clocks measure the aging process
- What role fasting and repair mechanisms play
- How epigenetic reprogramming could rejuvenate cells and organs
- Why longevity research is currently making enormous progress
If you want to learn how your lifestyle can influence your genes and what options modern longevity medicine offers, listen now!

